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化工儀器網(wǎng)>產(chǎn)品展廳>試劑標(biāo)物>行業(yè)專用試劑>生物試劑> JAZF1抗體JAZF1

JAZF1抗體JAZF1

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上海恒斐生物科技有限公司自2011年成立以來,,始終致力面向生命科學(xué)領(lǐng)域,,從事科研機構(gòu)及生產(chǎn)企業(yè)所需的各類生產(chǎn)原料、試劑,、儀器,、耗材等的專業(yè)進出口公司。自成立以來發(fā)展迅速,,產(chǎn)品服務(wù)得到全國廣大生產(chǎn)企業(yè),、高校、科研院所,、醫(yī)療系統(tǒng)及相關(guān)試劑公司的肯定,,*合作的客戶遍及全國各地。主要專注于生命科學(xué)和生物技術(shù)領(lǐng)域產(chǎn)品的研發(fā),、代理,、銷售為一體的資源性公司。

主營:蛇毒試劑,、高質(zhì)量脂蛋白,、培養(yǎng)基、抗體,、ELISA試劑盒,、生化試劑、標(biāo)準(zhǔn)溶液,、指示劑,、緩沖液等。

服務(wù):病理分析服務(wù),、病理技術(shù)服務(wù),、組織芯片服務(wù)。

抗體,,ELISA試劑盒,,生化試劑,脂蛋白,,蛇毒試劑,,標(biāo)準(zhǔn)溶液

訂購JAZF1抗體JAZF1及了解更多信息可以客服人員。


JAZF1抗體JAZF1主要參數(shù)>>>

中文名稱:  JAZF1抗體
英文名稱:  JAZF1
抗體別名:  JAZF zinc finger 1; JAZF1; JAZF1_HUMAN; Juxtaposed with another zinc finger protein 1; TAK1 interacting protein 27; TAK1-interacting protein 27; TIP27; Zinc finger protein 802; ZNF802.
抗體來源:  Rabbit
克隆類型:  Polyclonal
交叉反應(yīng):  Human,,Mouse,,Rat,Chicken,,Pig,,Horse,,Rabbit,Sheep,,
產(chǎn)品應(yīng)用:  WB=1:100-500ELISA=1:500-1000IHC-P=1:100-500IHC-F=1:100-500ICC=1:100-500IF=1:100-500
抗體濃度:  1mg/1ml
抗體性狀:  Lyophilized or Liquid
免 疫 原:   KLH conjugated synthetic peptide derived from human JAZF1
分 子 量:   27kDa
抗體亞型:  IgG
純化方法:  affinity purified by Protein A
細(xì)胞定位:  
研究領(lǐng)域:  
保存方法:
0.01M TBS(pH7.4) with 1% BSA,, 0.03% Proclin300 and 50% Glycerol.
Store at -20 °C for one year. Avoid repeated freeze/thaw cycles. The lyophilized antibody is stable at room temperature for at least one month and for greater than a year when kept at -20°C. When reconstituted in sterile pH 7.4 0.01M PBS or diluent of antibody the antibody is stable for at least two weeks at 2-4 °C.
產(chǎn)品介紹:
background:
This gene encodes a nuclear protein with three C2H2-type zinc fingers, and functions as a transcriptional repressor. Chromosomal aberrations involving this gene are associated with endometrial stromal tumors. Alternatively spliced variants which encode different protein isoforms have been described; however, not all variants have been fully characterized [provided by RefSeq, Jul 2008]

Function:
Potential transcription factor.

Subunit:
Interacts with TAK1.

DISEASE:
Note=A chromosomal aberration involving JAZF1 may be a cause of endometrial stromal tumors. Translocation t(7;17)(p15;q21) with SUZ12. The translocation generates the JAZF1-SUZ12 oncogene consisting of the N-terminus part of JAZF1 and the C-terminus part of SUZ12. It is frequently found in all cases of endometrial stromal tumors, except in endometrial stromal sarcomas, where it is rarer. Translocation t(6;7)(p21;p22) with PHF1.

Similarity:
Contains 3 C2H2-type zinc fingers.

Gene ID:
221895

Database links:

Entrez Gene: 221895 Human

Entrez Gene: 231986 Mouse

Entrez Gene: 685879 Rat

Omim: 606246 Human

SwissProt: Q86VZ6 Human

SwissProt: Q80ZQ5 Mouse

SwissProt: Q5RDF5 Orangutan

Unigene: 368944 Human

Unigene: 386865 Mouse



Important Note:
This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications.

II型糖尿病是危害很大的疾病,科學(xué)家們zui近又鑒定出了6個參與II型糖尿病有關(guān)的基因,。其中JAZF1基因同時在II型糖尿病和前列腺癌中都起作用,,但糖尿病和前列腺癌的變異處于基因的不同位置。這些研究將會幫助我們揭示復(fù)雜的糖尿病基礎(chǔ),,提示治療和預(yù)防這個疾病的更好新方法。{bios_back}{anti_back}{tongyogn_back}
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