Recombinant Human dCMP Deaminase
人Dcmp脫氨酶 （DCTD）
Catalogue Number  ENZ-538

Synonyms:
Deoxycytidylate deaminase, EC 3.5.4.12, dCMP Deaminase, DCTD, MGC111062. 

Introduction:
DCTD is an allosteric enzyme that exists as a homohexamer and is part of the cytidine and deoxycytidylate deaminase protein family. DTCD uses zinc as a cofactor to catalyze the deamination of dCMP to dUMP, thus making the nucleotide substrate （dUMP） that is used by thymidylate synthase. 

Description:
DCTD Recombinant Human produced in E.Coli is a single, non-glycosylated polypeptide chain containing 198 amino acids （1-178 a.a.） and having a molecular mass of 22.1 kDa. The DCTD is fused to 20 amino acid His-Tag at N-terminus and purified by proprietary chromatographic techniques. 

Source:
Escherichia Coli. 

Physical Appearance:
Sterile filtered colorless solution. 

Formulation:
DCTD Human solution containing 20mM Trsi pH-8, 1mM DTT, 1mM EDTA & 20% glycerol. 

Stability:
DCTD Human although stable at 4°C for 1 week, should be stored desiccated below -18°C. Please prevent freeze thaw cycles. 

Purity:
Greater than 90.0% as determined by SDS-PAGE. 

Amino acid sequence:
MGSSHHHHHH SSGLVPRGSH MSEVSCKKRD DYLEWPEYFM AVAFLSAQRS KDPNSQVGAC IVNSENKIVG IGYNGMPNGC SDDVLPWRRT AENKLDTKYP YVCHAELNAI MNKNSTDVKG CSMYVALFPC NECAKLIIQA GIKEVIFMSD KYHDSDEATA ARLLFNMAGV TFRKFIPKCS KIVIDFDSIN SRPSQKLQ. 

Usage:
ProSpec's products are furnished for LABORATORY RESEARCH USE ONLY. The product may not be used as drugs, agricultural or pesticidal products, food additives or household chemicals. 
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