S0B5515 PE-Cy7 Mouse Anti-Human CD123 Antibody (S-R442)
- 公司名稱 杭州斯達(dá)特生物科技有限公司
- 品牌 Starter/斯達(dá)特
- 型號(hào) S0B5515
- 產(chǎn)地 浙江 杭州
- 廠商性質(zhì) 生產(chǎn)廠家
- 更新時(shí)間 2025/6/11 9:28:45
- 訪問(wèn)次數(shù) 38
聯(lián)系方式:王修明13774214275 查看聯(lián)系方式
聯(lián)系我們時(shí)請(qǐng)說(shuō)明是化工儀器網(wǎng)上看到的信息,謝謝!
CD123, also known as the alpha chain of the interleukin-3 receptor (IL-3Rα), is a membrane-bound protein that plays a crucial role in immune regulation and hematopoiesis. It is overexpressed in various hematologic malignancies, including acute myeloid leukemia (AML), blastic plasmacytoid dendritic cell neoplasm (BPDCN), acute lymphoblastic leukemia (ALL), hairy cell leukemia, and systemic mastocytosis. The CD123 protein consists of three extracellular domains, a single-pass transmembrane domain, and a short intracellular region. It is involved in the growth, proliferation, survival, and differentiation of hematopoietic cells. CD123 is particularly significant as a biomarker for targeted therapy in these diseases, with various pharmacologic strategies and agents under investigation or already approved for clinical use. For instance, Tagraxofusp, an anti-CD123 antibody conjugated to diphtheria toxin, has been approved for use in patients with BPDCN.
相關(guān)分類
該廠商的其他產(chǎn)品
- S0B5521 Rabbit Anti-FMC63 Antibody (S-2163-77)
- S0B5522 Rat Anti-Mouse CD40 Antibody (S-R456)
- S0B5511 Rat Anti-Mouse CD107b (Mac-3) Antibody (S-R710)
- S0B5512 Rat Anti-Mouse IL-2 Antibody (S-R536)
- S0B5514 PE-Cy5 Rat Anti-Mouse CD4 Antibody (S-R382)
- S0B5516 PE-Cy7 Mouse Anti-Human HLA-DR Antibody (S-R566)
- S0B5517 PE-Cy7 Rat Anti-Mouse CD4 Antibody (S-R382)
- S0B5518 PE-Cy7 Rat Anti-Mouse F4/80 Antibody (S-R537)