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CRL-2713 MDA-kb2細(xì)胞,，人乳腺細(xì)胞

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型號(hào) CRL-2713
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人乳腺細(xì)胞 MDA-kb2細(xì)胞

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上海復(fù)祥生物科技有限公司是一家專業(yè)從事原代細(xì)胞,、細(xì)胞系；菌種,；及細(xì)胞因子相關(guān)產(chǎn)品的銷售企業(yè),。公司建有自己的細(xì)胞庫和菌種庫,。細(xì)胞庫管理規(guī)范，提供的細(xì)胞株背景清楚,，提供參考文獻(xiàn)和*培養(yǎng)條件,，公司引進(jìn)ATCC細(xì)胞500余種，ATCC菌種800余種,。并和國內(nèi)各大保藏中心有密切聯(lián)系,，細(xì)胞種類齊全，質(zhì)量保證,！是生命科學(xué)領(lǐng)域*的一部分,！

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ATCC 細(xì)胞,細(xì)胞系,細(xì)胞株,腫瘤細(xì)胞,細(xì)胞,ATCC 菌種，CMCC 菌種,，標(biāo)準(zhǔn)菌株,，質(zhì)控菌種，微生物菌種,，菌株,，菌種

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供貨周期	一周	規(guī)格	T25
貨號(hào)	MDA-kb2細(xì)胞	應(yīng)用領(lǐng)域	醫(yī)療衛(wèi)生,化工,生物產(chǎn)業(yè),制藥/生物制藥
主要用途	科學(xué)研究

MDA-kb2細(xì)胞，人乳腺細(xì)胞

ATCC^® Number:

CRL-2713™

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Designations:	MDA-kb2
Depositors:	VS Wilson
Biosafety Level:	1
Shipped:	frozen
Medium & Serum:	See Propagation
Growth Properties:	adherent
Organism:	Homo sapiens (human)
Morphology:	epithelial
Source:	Organ: mammary gland; breast Cell Type: epithelial
Cellular Products:	luciferase ( [57526] The cell line expresses firefly luciferase under control of the MMTV promoter that contains response elements for both glucocorticoid receptors (GR) and androgen receptors (AR).)
Permits/Forms:	In addition to the MTA mentioned above, other ATCC and/or regulatory permits may be required for the transfer of this ATCC material. Anyone purchasing ATCC material is ultimay responsible for obtaining the permits. Please click here for information regarding the specific requirements for shipment to your location.
MDA-kb2細(xì)胞,，人乳腺細(xì)胞
Isolation:	Isolation date: November 25, 1998
Applications:	assay of androgen receptor ( [57526] MDA-kb2 may be used in an in vitro assay to screen androgen agonist and antagonists and to characterize its specificity and sensitivity to endocrine disrupting chemicals.)
Receptors:	androgen receptor [57526] glucocorticoid receptor, positive [57526]
DNA Profile (STR):	Amelogenin: X CSF1PO: 10,12 D13S317: 12 D16S539: 9 D5S818: 11 D7S820: 10 THO1: 6 TPOX: 10 vWA: 17,18
Age:	48 years adult
Gender:	female
Ethnicity:	Caucasian
Comments:	Since both glucocorticoid receptor and androgen receptor are present in the MDA-MB-453 cells, and both receptors can act through the MMTV promoter, compounds that act through either androgen receptor or glucocorticoid receptor activate the MMTV luciferase reporter. Androgen receptor agonists such as dihydrotestosterone, and glucocorticoid receptor agonists such as dexamethasone, corticosterone, and aldosterone induce luciferase expression. Responsiveness of the cell line was monitored over time and was stable for more than 80 passages. The cell line is an in vitro tool for research in endocrine activity of the human androgen receptor and glucocorticoid receptor. It can be used to screen chemicals for both androgen receptor and glucocorticoid receptor mediated activities.
Propagation:	ATCC complete growth medium: The base medium for this cell line is ATCC-formulated Leibovitz's L-15 Medium, Catalog No. 30-2008. To make the complete growth medium, add the following components to the base medium: fetal bovine serum to a final concentration of 10%. Atmosphere: air, 100%
	parental cell line:ATCC HTB-131
References:	57526: Wilson VS, et al. A novel cell line, MDA-kb2, that stably expresses an androgen- and glucocorticoid-responsive reporter for the detection of hormone receptor agonists and antagonists. Toxicol. Sci. 66: 69-81, 2002. PubMed: 11861974

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