Anti-Human CD279 (PD-1) Biotin
- 公司名稱 上??泼羯锟萍加邢薰?/a>
- 品牌 EBioscience
- 型號
- 產(chǎn)地
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- 更新時間 2015/12/13 17:11:06
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Anti-Human CD279 (PD-1) Biotin ebioscience
產(chǎn)品名稱:Anti-Human CD279 (PD-1) Biotin ebioscience
產(chǎn)品貨號:13-2799-80
產(chǎn)品規(guī)格:25 ug
產(chǎn)品品牌:eBioscience
Details
Host | Mouse |
---|---|
Isotype | IgG1, kappa |
Reactivity | Human |
Conjugate | Biotin |
Reported Applications | Flow Cytometric Analysis |
Description
Description: The J105 monoclonal antibody reacts with the human PD-1 (programmed death-1), a 55 kDa member of the CD28 immunoglobulin superfamily. PD-1 contains the immunoreceptor tyrosine-based inhibitory motif (ITIM) and plays a key role in peripheral tolerance and autoimmune disease. PD-1 is expressed predominantly on activated T and B lymphocytes. Two novel members of the B7 family have been identified as the PD-1 ligands, PD-L1 (B7-H1) and PD-L2 (B7-DC). Evidence reported to date suggests overlapping functions for these two PD-1 ligands and their constitutive expression on some normal tissues and upregulation on activated antigen-presenting cells.
Costaining experiments suggest that eBioJ105 recognizes a different epitope than MIH4 (cat. 11-9969).
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