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AAT-21204 RatioWorks PDMPO

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AAT-21204RatioWorks PDMPO

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上海浩洋生物技術(shù)有限公司在為生命科學(xué)領(lǐng)域提供豐富的產(chǎn)品與信息資源方面處于全國*地位,公司提供的產(chǎn)品涵蓋了二十多個國家近五十萬種產(chǎn)品,,而且產(chǎn)品的數(shù)量與信息在不斷的增長和更新,,公司提供的產(chǎn)品能夠使生命科學(xué)工作者加快對生物化學(xué),分子生物學(xué),,細(xì)胞生物學(xué)以及蛋白質(zhì)組學(xué)研究的認(rèn)知,,以及分子診斷和臨床醫(yī)學(xué)領(lǐng)域的應(yīng)用。

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產(chǎn)品名稱:RatioWorks  PDMPO
產(chǎn)品價格:1140
產(chǎn)    地:AAT
產(chǎn)品貨號:21204
產(chǎn)品規(guī)格:1 mg
其它產(chǎn)品:
RatioWorks  PDMPO, SE 2340  AAT-21210 1 mg
RatioWorks  PDMPO Dextran 2340  AAT-21211 1 mg
產(chǎn)品說明:
The existing pH probes are ill-adapted to study acidic organelles such as lysosomes, endosomes, spermatozoa and acrosomes because their fluorescence is significantly reduced at lower pH. In addition, most of the existing pH probes (such as BCECF and SNARF) are not selectively localized in acidic organelles. The growing potential of ratio imaging is significantly limited by the lack of appropriate fluorescent probes for acidic organelles although ratio imaging has received intensive attention in the past few decades. PDMPO [2-(4-pyridyl)-5-((4-(2-dimethylaminoethylaminocarbamoyl)methoxy)phenyl)oxazole] is characterized as acidotropic dual-excitation and dual-emission pH probe. It emits intense yellow fluorescence at lower pH and gives intense blue fluorescence at higher pH. This unique pH-dependent fluorescence makes PDMPO an ideal pH probe for acidic organelles with pKa = 4.47. PDMPO selectively labels acidic organelles (such as lysosomes) of live cells and the two distinct emission peaks can be used to monitor the pH fluctuations of live cells in ratio measurements. Additionally, the very large Stokes shift and excellent photostability of PDMPO make PDMPO an excellent fluorescent acidotropic reagent for fluorescence imaging. The unique fluorescence properties of PDMPO might give researchers a new tool with which to study acidic organelles of live cells. PDMPO can be well excited by the violet laser at 405 nm for flow cytometric applications.



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