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南京科佰生物科技有限公司
主營產品： atcc代理,ATCC細胞系,ATCC細胞株,ATCC細胞庫購買 |
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聯(lián)系電話
|
南京科佰生物科技有限公司
主營產品： atcc代理,ATCC細胞系,ATCC細胞株,ATCC細胞庫購買 |
聯(lián)系電話
| 參考價 | 面議 |
更新時間：2025-01-15 13:44:38瀏覽次數(shù)：1044
聯(lián)系我們時請說明是化工儀器網上看到的信息，謝謝!
| CBP71405 | |
| I. Background | |
GLP1R binds specifically the glucagon-like peptide-1 (GLP1) and has much lower affinity for related peptides such as the gastric inhibitory polypeptide and glucagon. GLP1R is known to be expressed in pancreatic beta cells. Activated GLP1R stimulates the adenylyl cyclase pathway which results in increased insulin synthesis and release of insulin. Consequently, GLP1R has been suggested as a potential target for the treatment of diabetes. GLP1R is also expressed in the brain where it is involved in the control of appetite. Furthermore, mice which over express GLP1R display improved memory and learning. | |
| II. Introduction | |
| Host Cell: | BHK |
| Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
| Synonym(s): | GLP1R |
| Freeze Medium: | 90% FBS+10% DMSO |
| Culture Medium: | MEM +10% FBS+ 1% Non Essential Amino Acids (NEAA)+ 1 mM sodium pyruvate+2ug/ml puromycin+500ug/ml Hygromycin B |
| Mycoplasma Status: | Negative |
| Storage: | Liquid nitrogen immediately upon delivery |
| Application(s): | Functional assay for GLP1R receptor |
| Transducer: | Gs |
| Ⅲ. Description of Host Cell Line | |
| Organism: | Mesocricetus auratus, hamster, Syrian golden |
| Tissue: | kidney |
| Disease: | Normal |
| Morphology: | fibroblast |
| Growth Properties: | Adherent |
| Ⅳ.Representative Data | |
Figure 1.GLP1R/CRE Reporter -BHK Recombinant Cell Line (C22). | |
