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美國布魯克海文儀器公司>技術文章>ZetaPlus Zeta電位測量應用案例-14

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ZetaPlus Zeta電位測量應用案例-14

閱讀:388          發(fā)布時間:2014-8-15
 文獻名: Protein Separations Using Colloidal Magnetic Nanoparticles
 
作者: Seyda Bucak, Deverraux A. Jones, Paul E. Laibinis and T. Alan Hatton
Department of Chemical Engineering, Massachusetts Institute of Technology, Cambridge, Massachusetts 02139
 
摘要: Phospholipid-coated colloidal magnetic nanoparticles with mean magnetite core size of 8 nm are shown to be effective ion exchange media for the recovery and separation of proteins from protein mixtures. These particles have high adsorptive capacities (up to 1200 mg protein/mL adsorbent, an order of magnitude larger than the best commercially available adsorbents) and exhibit none of the diffusional resistances offered by conventional porous ion exchange media. Protein-laden particles are readily recovered from the feed solution using high-gradient magnetic filtration.
 

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