Male Wistar rats (200-250 g); 10 mg/kg Indomethacin subcutaneous injection (s.c) for 9 consecutive days[1].
胃潰瘍模型
HY-14654 Aspirin 阿司匹林
Adult male albino mice (~25 g); 500 mg/kg Aspirin single oral administration (p.o)[2].
炎癥性腸病(IBD)模型
HY-126360 Oxazolone (OXA)
C57BL/6J mice (8-10 weeks); 5 μL/g 5% OXA [3]
炎癥性腸?。↖BD)/結(jié)腸腫瘤模型
HY-116282C Dextran sulfate sodium salt(DSS)
Mice were treated with an intraperitoneal injection of a single dose of AOM (12 mg/kg). After 3 days, 2% DSS dissolved in the drinking water was administered for 6 days (the DSS solution was refreshed on day 3), followed by 15 days of regular drinking water[4].
十二指腸潰瘍模型
HY-77591 Cysteamine hydrochloride 半胱胺鹽酸鹽
Male albino Wistar rats (Rattus norvegicus), 300 mg/kg Cysteamine hydrochloride, p.o. twice (5 mL/kg) in a 4-h interval induction[5].
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