Bag1 mouse mAb
抗體,也叫免疫球蛋白(Ig),,是一種能特異性結(jié)合抗原的糖蛋白,,而抗原是在易感染動物體內(nèi)引發(fā)抗體產(chǎn)生的物質(zhì)。在體內(nèi),,抗體是由于外源性分子的侵襲而產(chǎn)生的,。抗體以一個或者多個Y字形單體存在,,每個Y字形單體由4條多肽鏈組成,,包含兩條相同的重鏈和兩條相同的輕鏈,。輕鏈和重鏈是根據(jù)它們的分子量大小來命名的。Y字形結(jié)構(gòu)的頂端是可變區(qū),,為抗原結(jié)合部位,。任何一個抗體的輕鏈都可以分為κ或λ型(基于小分子多肽結(jié)構(gòu)上的差異),每一個抗體的重鏈則決定了它的類或型,。
免疫原詳細信息
Purified recombinant human Bag1 protein fragments expressed in E.coli.
相關(guān)試劑
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
背景
The oncogene BCL2 is a membrane protein that blocks a step in a pathway leading to apoptosis or programmed cell death. The protein encoded by this gene binds to BCL2 and is referred to as BCL2-associated athanogene. It enhances the anti-apoptotic effects of BCL2 and represents a link between growth factor receptors and anti-apoptotic mechanisms. Multiple protein isoforms are encoded by this mRNA through the use of a non-AUG (CUG) initiation codon, and three alternative downstream AUG initiation codons. A related pseudogene has been defined on chromosome X. [provided by RefSeq, Feb 2010]
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備注:圖片僅供參考,。僅供科研,不可用于臨床,。