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| 品牌 | 貨號 | 品名 | 規(guī)格 |
| Quidel | 8007 | Quidel MicroVue DPD EIA | 96 Test |
產(chǎn)品描述 | The Quidel MicroVue DPD EIA offers a laboratory test that measures deoxypyridinoline cross-links (Dpd), a specific marker of bone resorption which is excreted in the urine. MicroVue DPD EIA provides a quantitative measure of deoxypyridinoline (Dpd), a cross-link of bone type 1 collagen released during the resorption process. Dpd is excreted unmetabolized in urine. Elevated levels of urinary Dpd indicate elevated bone resorption in individuals. MicroVue DPD is a urinary assay that provides a quantitative measure of the excretion of deoxypyridinoline (DPD) crosslinks as an indicator of bone resorption. Elevated levels of urinary DPD indicate elevated bone resorption in individuals. Measurement of DPD is intended for use as an aid in monitoring bone resorption changes in postmenopausal women receiving hormonal or bisphosphonate antiresorptive therapies and in individuals diagnosed with osteoporosis. | ||
| 格式 | ELISA | ||
| 測試/套件 | 96-well microplate with reagents sufficient to test 40 samples in duplicate | ||
| 樣品類型 | 尿 | ||
| 物種反應(yīng)性 | 大鼠、小鼠,、兔,、豚鼠,、狗、豬,、羊、牛,、馬、松鼠,、食蟹猴、恒河猴,、人類細(xì)胞培養(yǎng) | ||
| 性能特點 | 方法：Competitive 分析物：脫氧吡啶啉交聯(lián) 樣品：尿液 樣品體積：50 µL 靈敏度：1.1 nM/L 動態(tài)范圍：3-300 nM 運行內(nèi)精密 CV：4%-8% 運行間精密 CV：3%- 5% 孵育時間：3 小時 交叉反應(yīng)性： 游離 Dpd 100% 游離 Pyd：< 1% Pyd/Dpd 肽：< 2.5% 預(yù)期值： 女性：25-44 歲,。絕經(jīng)前：3.0-7.4 nmol Dpd/mmol Cr 男性：25-55 歲：2.3-5.4 nmol Dpd/mmol Cr | ||
參考文獻(xiàn)：
1. Seyedin S.M., Rosen D.M. Matrix Proteins of the Skeleton. Curr. Opin. Cell Biol. 1990;2:914-919.
2. Delmas P.D. Biochemical markers for the assessment of bone turnover. In: Riggs BL, Melton LJ,III (eds):Osteoporosis: etiology, diagnosis, and management. Philadelphia: Lippincott-Raven Publishers, 1995, pp. 319- 333.
3. Seibel M.J., Robins S.P., Bilezikian J.P. Urinary pyridinium crosslinks of collagen. Specific markers of bone resorption in metabolic bone disease. Trends Endocrinol. Metab. 1992;3:263-270
