baseclick代理產(chǎn)品之BCFA-246-5mg,，Tri-β-GalNAc-PEG3-Azide

Tri-β-GalNAc-PEG3-Azide


Tri-β-GalNAc-PEG3-Azide 可通過銅催化疊氮化物-炔烴化學(xué) (CuAAC) 用 Tri-GalNAc 部分點(diǎn)擊標(biāo)記炔烴或 DBCO 修飾靶標(biāo),。Tri-GalNAc 結(jié)構(gòu)可被去唾液酸糖蛋白受體 (ASGPR) 識(shí)別,，因此可用于將生物分子作為 siRNA 靶向遞送至肝臟組織,。

Tri-β-GalNAc-PEG3-Azide enables the possibility to click label an Alkyne or DBCO modified target with an Tri-GalNAc moiety by copper-catalyzed Azide-Alkyne Chemistry (CuAAC). The Tri-GalNAc structure is recognized by the desialic acid glycoprotein receptor (ASGPR) and can be therefore used to target delivery of biomolecules as siRNA to liver tissue.

• Molecular Formula

  C₇₀H₁₂₅N₁₃O₃₁

• Shelf Life

  12 months unopened after receipt

• Storage Conditions

  -20 °C, dark

• Molecular Weight

  1644.8 g/mol

• Purity

  ≥ 95% (HPLC)

• Physical State

  white solid

• CAS Number

  n.a.

• Additional name

  Tri-β-GalNAc-PEG3-N3, (β-D-GalNAc)3-PEG3-N3, (β-D-GalNAc-sp)3-NHC(O)-PEG3-N3

• Solubility

  H2O, DMSO

• Preparation/Handling

  For a 10 mM solution add 304 μL to 5 mg.
  For a 10 mM solution add 608 μL to 10 mg.