日韩av大片在线观看欧美成人不卡|午夜先锋看片|中国女人18毛片水多|免费xx高潮喷水|国产大片美女av|丰满老熟妇好大bbbbbbbbbbb|人妻上司四区|japanese人妻少妇乱中文|少妇做爰喷水高潮受不了|美女人妻被颜射的视频,亚洲国产精品久久艾草一,俄罗斯6一一11萝裸体自慰,午夜三级理论在线观看无码

HGF R, also known as Met, is a glycosylated receptor tyrosine kinase that plays a pivotal role in epithelial morphogenesis and cancer development. It is synthesized as a single-chain precursor, which undergoes cotranslational proteolytic cleavage to form a mature HGFR. This mature receptor is a disulfide-linked dimer consisting of a 50 kDa extracellular alpha chain and a 145 kDa transmembrane beta chain. The extracellular domain （ECD） features a seven-bladed beta-propeller sema domain, a cysteine-rich PSI/MRS domain, and four Ig-like E-set domains. The cytoplasmic region contains the tyrosine kinase domain. HGFR is typically expressed by cells of epithelial origin, while HGF expression is limited to cells of mesenchymal origin.