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IL2RA is a protein that in humans is encoded by the IL2RA gene.Normally an integral-membrane protein, soluble IL2RA has been isolated and determined to result from extracellular proteolysis. Quantification of sIL-2RA is a useful and simple tool for clinicians to assess immune function in vivo as part of the investigation, management, and prognosis of a broad spectrum of diseases, such as sarcoidosis, Multiple Sclerosis, primary biliary cirrhosis, Chronic immune activation in common variable immunodeficiency （CVID）, chronic liver diseases and many more.