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Rat Insulin-like Growth Factor-1 （IGF-1） is a key regulatory protein involved in growth, metabolism, and cellular repair. Structurally homologous to human and mouse IGF-1, it binds to the IGF-1 receptor （IGF-1R） to activate downstream signaling pathways such as PI3K/Akt and MAPK, promoting cell proliferation, differentiation, and survival. Rat IGF-1 is widely utilized in research to investigate growth disorders, metabolic diseases, tissue regeneration, and aging processes in rat models. Recombinant rat IGF-1, produced in E. coli or mammalian expression systems, ensures high biological activity and consistency for experimental applications. It is particularly valuable in studies related to diabetes, neuroprotection, muscle development, and wound healing.