目錄:杭州斯達特生物科技有限公司>>抗體/抗原>>偶聯(lián)抗體>> S0B1543EpCAM/CD326 Recombinant Rabbit mAb (Alexa Fluor? 488 Conjugate) (S-1009-76)
Epithelial cell adhesion molecule （EpCAM）, also known as CD326 among other names, is a transmembrane glycoprotein mediating Ca2+-independent homotypic cell–cell adhesion in epithelia. EpCAM is also involved in cell signaling, migration, proliferation, and differentiation. Additionally, EpCAM has oncogenic potential via its capacity to upregulate c-myc, e-fabp, and cyclins A & E. Since EpCAM is expressed exclusively in epithelia and epithelial-derived neoplasms, EpCAM can be used as diagnostic marker for various cancers. It appears to play a role in tumorigenesis and metastasis of carcinomas, so it can also act as a potential prognostic marker and as a potential target for immunotherapeutic strategies.
1
化工儀器網