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CD11b, also known as Integrated alpha-m, a transgender protein, can form an heterododerous composed of α and β subunit. It is a common bone marrow mark （neutral granulocyte, monocyte, macrophage, and small gel cells） and NK （natural kill cells） antigens. It can be used to distinguish between acute granulocyte deficiency （CD11B+, CD117--） and acute early early early elastic cell leukemia （CD11B-, CD117+）.