目錄:杭州斯達(dá)特生物科技有限公司>>抗體/抗原>>流式抗體>> S0B5275Alexa Fluor? 488 Mouse Anti-Human CD184 Antibody (S-R635)
參考價(jià) | ¥ 1257 |
參考價(jià) | ¥ 1257 |
更新時(shí)間:2025-06-11 09:27:34瀏覽次數(shù):21評(píng)價(jià)
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CD184, also known as CXCR4 or fusin, is a 45 kD seven-transmembrane G-protein-linked CXC chemokine receptor. It is widely expressed on various human cells, including leukocytes, hematopoietic stem cells, epithelial cells, endothelial cells, and cancer cells. This receptor is specific for stromal-derived factor-1 (SDF-1, also called CXCL12) and plays a crucial role in cell migration, hematopoiesis, cell homing, and the proliferation of non-hematopoietic cells. Additionally, CXCR4 serves as a co-receptor for T-cell tropic HIV viruses, enabling their entry into human lymphocytes. In cancer, CXCR4 is involved in tumor cell survival, proliferation, migration, and metastasis, making it a potential therapeutic target.
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