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TCEP hydrochloride

MCE 國(guó)際站：TCEP hydrochloride

品牌：MedChemExpress (MCE)

貨號(hào)：HY-W011500

CAS：51805-45-9

Synonyms：Tris(2-?carboxyethyl?phosphine hydrochloride

純度：0.9918

存儲(chǔ)條件：4°C,，避光，氮?dú)獗４?*溶劑中：-80°C,，6 個(gè)月,；-20°C，1 個(gè)月（避光,，氮?dú)獗４妫?/p>

運(yùn)輸條件：美國(guó)大陸的室溫,；其他地方可能有所不同。

產(chǎn)品活性：TCEP hydrochloride (Tris(2-carboxyethyl)phosphine hydrochloride) 是一種非硫醇還原劑,，比其他化學(xué)還原劑更穩(wěn)定并且產(chǎn)生更快的 S-S 還原反應(yīng),。TCEP hydrochloride 是一種三烷基膦，可選擇性地減少蛋白質(zhì)的分解,，而不會(huì)改變其性質(zhì)或與反應(yīng)混合物中的硫醇導(dǎo)向劑發(fā)生相互作用,。TCEP hydrochloride 還是 DNA/AuNP 化學(xué)中常用的還原劑。

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參考文獻(xiàn)：

[1]. Dieguez-Acu?a FJ, et al. Inhibition of NF-kappaB-DNA binding by mercuric ion: utility of the non-thiol reductant, tris(2-carboxyethyl)phosphine hydrochloride (TCEP), on detection of impaired NF-kappaB-DNA binding by thiol-directed agents. Toxicol In Vitro. 2000 Feb;14(1):7-16.[2]. Duchardt F, et al. A cell-penetrating peptide derived from human lactoferrin with conformation-dependent uptake efficiency. J Biol Chem. 2009 Dec 25;284(52):36099-108.[3]. Sequeira MA, et al. Modulating amyloid fibrillation in a minimalist model peptide by intermolecular disulfide chemical reduction. Phys Chem Chem Phys. 2019 Jun 5;21(22):11916-11923.[4]. Wu R, et al. Effects of Small Molecules on DNA Adsorption by Gold Nanoparticles and a Case Study of Tris(2-carboxyethyl)phosphine (TCEP). Langmuir. 2019 Oct 15;35(41):13461-13468.[5]. Han JC, Han GY. A procedure for quantitative determination of tris(2-carboxyethyl)phosphine, an odorless reducing agent more stable and effective than dithiothreitol. Anal Biochem. 1994;220(1):5-10.