RARγ Luciferase Reporter HEK293 Cell Line is a HEK293 cell line engineered to express firefly luciferase, under the control of retinoic acid response elements (RARE), and with full length human RARγ (retinoic acid receptor gamma) (accession # P13631-1). RARγ Luciferase Reporter HEK293 Cell Line is designed for monitoring the activity of RARγ. This cell line was functionally validated by stimulation with all-trans retinoic acid and Western Blot analysis.

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Figure 1: Illustration of the mechanism of action of RARγ Luciferase Reporter HEK293 Cell Line. Upon activation with retinoic acid, RAR dimerizes with RXR, and activates RARE and luciferase expression. The level of activation corresponds directly to the luciferase signal.

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