TRADD Polyclonal Antibody
抗體,,也叫免疫球蛋白(Ig),是一種能特異性結(jié)合抗原的糖蛋白,,而抗原是在易感染動(dòng)物體內(nèi)引發(fā)抗體產(chǎn)生的物質(zhì),。在體內(nèi),抗體是由于外源性分子的侵襲而產(chǎn)生的,??贵w以一個(gè)或者多個(gè)Y字形單體存在,每個(gè)Y字形單體由4條多肽鏈組成,,包含兩條相同的重鏈和兩條相同的輕鏈,。輕鏈和重鏈?zhǔn)歉鶕?jù)它們的分子量大小來(lái)命名的。Y字形結(jié)構(gòu)的頂端是可變區(qū),,為抗原結(jié)合部位,。任何一個(gè)抗體的輕鏈都可以分為κ或λ型(基于小分子多肽結(jié)構(gòu)上的差異),每一個(gè)抗體的重鏈則決定了它的類或型,。
The protein encoded by this gene is a death domain containing adaptor molecule that interacts with TNFRSF1A/TNFR1 and mediates programmed cell death signaling and NF-kappaB activation. This protein binds adaptor protein TRAF2, reduces the recruitment of inhibitor-of-apoptosis proteins (IAPs) by TRAF2, and thus suppresses TRAF2 mediated apoptosis. This protein can also interact with receptor TNFRSF6/FAS and adaptor protein FADD/MORT1, and is involved in the Fas-induced cell death pathway. [provided by RefSeq, Jul 2008]
備注:圖片僅供參考,。僅供科研,不可用于臨床,。