非布司他雜質(zhì) 非布索坦雜質(zhì)申報(bào)

時(shí)間：2017/3/2閱讀：1199

非布司他適應(yīng)癥及作用機(jī)理：非布司他主要成份為非布佐司他,，其化學(xué)名為2-[(3-氰基-4-異丁氧基)苯基]-4-甲基-5-噻唑羧酸,。為黃嘌呤氧化酶（XO）抑制劑,，適用于具有痛風(fēng)癥狀的高尿酸血癥的長(zhǎng)期治療。非布佐司他是黃嘌呤氧化酶抑制劑,，通過(guò)減少血清尿酸達(dá)到療效。本品在治療濃度下不會(huì)抑制嘌呤和嘧啶的合成及代謝過(guò)程中的其他酶,。

深圳遠(yuǎn)揚(yáng)化學(xué)技術(shù)有限公司提供的非布司他雜質(zhì)純度高,，來(lái)源正規(guī)，*非布司他新藥申報(bào)的要求,，隨貨提供COA證書(shū),，氫譜,，質(zhì)譜及HPLC，,。（請(qǐng)點(diǎn)擊本頁(yè)標(biāo)題下方“進(jìn)入該公司展臺(tái)” 查看我司信息）,。

Febuxostat	2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid
Febuxostat Impurity 1	ethyl 2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Febuxostat Impurity 2	ethyl 2-(3-formyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
Febuxostat Impurity 3	ethyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
Febuxostat Impurity 4	2-(3-carbamoyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid
Febuxostat Impurity 5	ethyl 2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Febuxostat Impurity 6	(E)-ethyl 2-(3-((hydroxyimino)methyl)-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
Febuxostat Impurity 7	(E)-2-(3-((hydroxyimino)methyl)-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid
Febuxostat Impurity 8	2-(3-formyl-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid
Febuxostat Impurity 9	2-(3-cyano-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid
Febuxostat Impurity 10	2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid 1-oxide
Febuxostat Impurity 11	2-(3-carboxy-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid
Febuxostat Impurity 12	4-isobutoxybenzene-1,3-bis(carbothioamide)
Febuxostat Impurity 13	dimethyl 2,2'-(4-isobutoxy-1,3-phenylene)bis(4-methylthiazole-5-carboxylate)
Febuxostat Impurity 14	2-isobutoxy-5-(4-methylthiazol-2-yl)benzonitrile
Febuxostat Impurity 15	2-(4-butoxy-3-cyanophenyl)thiazole-5-carboxylic acid
Febuxostat Impurity 16	2-(4-(sec-butoxy)-3-cyanophenyl)thiazole-5-carboxylic acid
Febuxostat Impurity 17	2-(3-cyano-4-propoxyphenyl)thiazole-5-carboxylic acid
Febuxostat Impurity 18	ethyl 2-(4-hydroxy-3-vinylphenyl)-4-methylthiazole-5-carboxylate
Febuxostat Impurity 19	ethyl 2-(2-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Febuxostat Impurity 20	2,2'-(4-isobutoxy-1,3-phenylene)bis(4-methylthiazole-5-carboxylic acid)
Febuxostat Impurity 21	diethyl 2,2'-(4-isobutoxy-1,3-phenylene)bis(4-methylthiazole-5-carboxylate)
Febuxostat Impurity 22	ethyl 2-(4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
Febuxostat Impurity 23	2-(3-formyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid
Febuxostat Impurity 24	2-(4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid
Febuxostat Impurity 25	2-(3-carboxy-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid
Febuxostat Impurity 26	2-(3-carbamoyl-4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid
Febuxostat Impurity 27	2-(4-butoxy-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid
Febuxostat Impurity 28	2-(4-(sec-butoxy)-3-cyanophenyl)-4-methylthiazole-5-carboxylic acid
Febuxostat Impurity 29	2-(3-cyano-4-propoxyphenyl)-4-methylthiazole-5-carboxylic acid
Febuxostat Impurity 30	2-(3-cyano-4-ethoxyphenyl)-4-methylthiazole-5-carboxylic acid
Febuxostat Impurity 31	(E)-ethyl 2-(4-hydroxy-3-((hydroxyimino)methyl)phenyl)-4-methylthiazole-5-carboxylate
Febuxostat Impurity 32	ethyl 2-(3-formyl-2-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Febuxostat Impurity 33	2-(3-cyano-4-isopropoxyphenyl)-4-methylthiazole-5-carboxylic acid
Febuxostat Impurity 34	isopropyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
Febuxostat Impurity 35	methyl 2-(3-cyano-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylate
Febuxostat Impurity 36	2-(3-bromo-4-isobutoxyphenyl)-4-methylthiazole-5-carboxylic acid
Febuxostat Impurity 37	ethyl 2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylate
Febuxostat Impurity 38	2-(4-hydroxyphenyl)-4-methylthiazole-5-carboxylic acid

非布司他雜質(zhì) 非布索坦雜質(zhì)申報(bào)

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