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深圳欣博盛生物科技有限公司
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當(dāng)前位置:深圳欣博盛生物科技有限公司>>抗體>>內(nèi)參抗體>> InVivoMab anti-mouse CD25 (IL-2Rα)

InVivoMab anti-mouse CD25 (IL-2Rα)

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產(chǎn)品型號

品       牌BioxCell

廠商性質(zhì)代理商

所  在  地深圳市

更新時間:2022-01-27 14:01:21瀏覽次數(shù):521次

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供貨周期 一個月 規(guī)格 5mg
貨號 BE0012-5MG 應(yīng)用領(lǐng)域 生物產(chǎn)業(yè)
主要用途 科研
The PC-61.5.3 monoclonal antibody reacts with mouse IL-2Rα also known as CD25, Ly-43, p55, or Tac. IL-2Rα is the 55 kDa ligand-binding subunit of the interleukin 2 receptor alpha chain.

The PC-61.5.3 monoclonal antibody reacts with mouse IL-2Rα also known as CD25, Ly-43, p55, or Tac. IL-2Rα is the 55 kDa ligand-binding subunit of the interleukin 2 receptor alpha chain. IL-2Rα is expressed on activated mature T and B lymphocytes, thymocyte subsets, pre-B cells, and T regulatory cells. IL-2Rα has been shown to play roles in lymphocyte differentiation, activation, and proliferation. Alone, the IL-2Rα binds IL-2 with relatively low affinity however, when IL-2Rα associates with IL-2Rβ (CD122) and the common gamma chain (CD132) the complex binds IL-2 with high affinity. The PC-61.5.3 antibody has been shown to inhibit the binding of IL-2 to both the low and high affinity IL-2 receptor forms. Additionally, the PC-61.5.3 antibody is commonly used to deplete CD4+FoxP3+ T regulatory cells in vivo.


產(chǎn)品名稱:InVivoMab anti-mouse CD25 (IL-2Rα)

反應(yīng)種屬:mouse

宿主來源:rat

實驗應(yīng)用:in vivo regulatory T cell depletion, Flow cytometry

同種型:IgG1, λ

免疫原:IL-2-dependent cytolytic mouse T cell clone B6.1

克隆性:Monoclonal

克隆號:PC-61.5.3

產(chǎn)品濃度:Lot specific,typically between 4-11 mg/ml

保存溫度:Undiluted at 4°C in the dark

運輸溫度:Ship with adequate amount of blue ice to ensure the product remains at 4°C for the duration of transit

預(yù)期分子量:150 kDa

產(chǎn)品形式:液體

有效期:One year from the date of receipt if stored as recommended

產(chǎn)地:美國


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