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南京科佰生物科技有限公司

當(dāng)前位置:南京科佰生物科技有限公司>>藥靶細(xì)胞株>>GPCR細(xì)胞株>> CBP71363CCR8/β-Arrestin/CHO GPCR細(xì)胞

CCR8/β-Arrestin/CHO GPCR細(xì)胞

參  考  價(jià):面議
具體成交價(jià)以合同協(xié)議為準(zhǔn)

產(chǎn)品型號(hào)CBP71363

品牌cobioer/科佰生物

廠商性質(zhì)代理商

所在地南京市

更新時(shí)間:2022-09-02 15:46:21瀏覽次數(shù):1189次

聯(lián)系我時(shí),,請(qǐng)告知來自 化工儀器網(wǎng)
供貨周期 現(xiàn)貨 規(guī)格 T-25 Flask
貨號(hào) CBP71363 應(yīng)用領(lǐng)域 生物產(chǎn)業(yè)
CCR8/β-Arrestin/CHO
CBP71363
I. Background

C-C chemokine receptor type 1 (CCR8) is a G protein-coupled receptor member of the CC chemokine subfamily of
receptors. Following interaction with its specific chemokine ligands, like macrophage inflammatory protein 1 alpha
(MIP-1 alpha), regulated on activation normal T expressed and secreted protein (RANTES), and monocyte
chemoattractant protein 3 (MCP-3), it triggers the onset of a process known as chemotaxis. GenScript’s human
CCR8-expressing stable subline is guaranteed to function properly in the calcium flux assay.

 
II. Introduction
Host Cell:

CHO

Stability:20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.)
Freeze Medium:90% FBS+10% DMSO
Culture Medium:N/A
Mycoplasma Status:Negative
Storage:Liquid nitrogen immediately upon delivery
Application(s):

Functional assay for CCR8 receptor

Transducer:Gi
 
Ⅲ. Description of Host Cell Line
Organism:Hamster
Tissue:Ovary
Morphology: Epithelial
Growth Properties: Adherent
 
Ⅳ. Representative Data

CBP71363.png

Figure 1. Dose response of Human Recombinant CCL1 in CCR8 β-Arrestin/CHO-K1 Cell Line (C6).

CBP71363 數(shù)據(jù)圖2.png

Figure 2. Inhibition of CCL1-induced Beta-Arrestin Recruitment By CCR8 Blocking Ab in CCR8 Beta-Arrestin CHO-K1 Cells.

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