CBP71342 | |
I. Background | |
There are 3 alpha-1 adrenergic receptor subtypes: alpha-1A, -1B and -1D, all of which signal through the Gq/11 family of G-proteins and different subtypes show different patterns of activation. They activate mitogenic responses and regulate growth and proliferation of many cells. | |
II. Introduction | |
Host Cell: | HEK293 |
Stability: | 20 passages (in-house test, that not means the cell line will be instable beyond the passages we tested.) |
Freeze Medium: | 90% FBS+10% DMSO |
Culture Medium: | DMEM+10%FBS+400ug/ml G418 |
Mycoplasma Status: | Negative |
Storage: | Liquid nitrogen immediately upon delivery |
Application(s): | Functional assays for alpha1DAR receptor |
Transducer: | Gq |
Ⅲ. Description of Host Cell Line | |
Organism: | Human |
Tissue: | kidney |
Morphology: | Epithelial |
Growth Properties: | Adherent |
Ⅳ. Representative Data |