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微波輻射可提高菲啶的合成產(chǎn)量
閱讀:1708發(fā)布時間:2012-10-24
Microwave irradiation dramatically increases the isolated yield of an alkyne cyclotrimerization step when compared to conventional heating methods. The flexibility of being able to perform a reaction in either an open or sealed vessel format provides the ability to add all reagents at the start of the reaction to take advantage of a high temperature/high pressure environment or add reagents during the reaction, reducing byproduct formation.
與傳統(tǒng)加熱方法相比,,微波輻射大大增加了alkyne cyclotrimerization分離產(chǎn)量,。在敞口和密封的條件下,,均可進行反應(yīng),。在反應(yīng)開始前,,可添加所有試劑反應(yīng)試劑,,在高溫高壓環(huán)境或添加試劑反應(yīng)時,減少副產(chǎn)物的形成,。
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