C1酯酶抑制劑

時(shí)間：2018/7/30閱讀：1108

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Athens Research & Technology自1986年以來一直在凈化人類蛋白質(zhì)和開發(fā)這些蛋白質(zhì)的多克隆抗血清,。我們專注于高純度,，高活性的人類蛋白質(zhì)。我們常規(guī)純化絲氨酸蛋白酶,，蛋白酶抑制劑,，中性粒細(xì)胞酶，載脂蛋白,，脂蛋白,，血小板蛋白,，轉(zhuǎn)鐵蛋白，免疫球蛋白等,。世界各地的研究人員已經(jīng)從我們這里購買了這些研究試劑超過二十五年,。您將看到我們的產(chǎn)品在炎癥，冠心病,，自身免疫性疾病,，癌癥，阿爾茨海默病等研究的主要科學(xué)出版物中被引用,。

我們還從動(dòng)物血清和組織中分離蛋白質(zhì),。

我們的產(chǎn)品被診斷和制藥行業(yè)的先進(jìn)者用作體外診斷和免疫測定試劑盒的組分，以及細(xì)胞培養(yǎng)基,，包括支持干細(xì)胞的培養(yǎng)基,。雅典研究和技術(shù)的蛋白質(zhì)也被開發(fā)生物治療藥物的研究人員用于概念驗(yàn)證研究。

C1酯酶抑制劑,，人血漿

產(chǎn)品編號(hào)：

16-16-031509

MW：100,000
消光系數(shù)：0.4

用含有250mMpotassium phosphate的20mM磷酸鉀（pH7.0）冷凍

儲(chǔ)存：-70°C或更低

購買純化的天然人C1酯酶抑制劑,，人血漿。
批量數(shù)量可用,。

單鏈糖蛋白,，抑制C1，C1r,，C1s,，血漿激肽釋放酶，因子XIa,。XIIa和纖溶酶,。以每100毫升16-33毫克存在于血漿中。C1酯酶抑制劑缺乏是一種罕見的病癥,，導(dǎo)致面部腫脹和腹部絞痛,。通常情況是遺傳性的，盡管它也可能在C1EI無功能時(shí)發(fā)生,。

純度：通過SDS-PAGE> = 95％

同義詞：補(bǔ)體C1酯酶抑制劑,，酯酶抑制劑C-1

通過FDA批準(zhǔn)的測試，血漿制備顯示對(duì)HbsAG,，抗-HCV,，抗-HBc無反應(yīng)，對(duì)抗-HIV 1和2呈陰性,。

雅典研究與技術(shù)產(chǎn)品是實(shí)驗(yàn)室試劑,，不得用于人體或用于任何藥物目的。僅供研究或進(jìn)一步制造使用。

產(chǎn)品引用：

Salvesen,，GS等人,。1985. J. Biol?；瘜W(xué),。260,2432。

Lee,，Kyoung Geun,，Haneulnari Lee，Jeong Mi Ha,，Young Kyung Lee,，Hee Jung Kang，Chung-Gyu Park和Sang Joon Kim,。“增加的人腫瘤壞死因子-α水平在體外誘導(dǎo)豬內(nèi)皮細(xì)胞的促凝血改變,。”異種移植19，沒有,。3（2012）：186-195

Kang,，Hee Jung，Haneulnari Lee,，Jeong-mi Ha,，Jae-il Lee，Jun-Seop Shin,，Ki-Yong Kim,，Ji Yoon Park et al。“替代補(bǔ)體途徑在門靜脈內(nèi)豬胰島異種移植后早期移植物丟失中的作用,。” 移植（2014年）

Kenninston JA,，et al。高特異性活性位點(diǎn)阻斷抗體對(duì)血漿激肽釋放酶的抑制作用,。J Biol Chem,。2014年8月22日; 289（34）：23596-608。doi：10.1074 / jbc.M114.569061,。Epub 2014年6月26日,。

Zamolodchikov D，Renner T,，Strickland S.
阿爾茨海默氏病肽β-淀粉樣蛋白通過激活凝血因子XII促進(jìn)凝血酶的產(chǎn)生,。
J Thromb Haemost,。2016年5月; 14（5）：995-1007,。doi：10.1111 / jth.13209。Epub
2016年2月29日。

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C1酯酶抑制劑

C1酯酶抑制劑,，人血漿

產(chǎn)品編號(hào)：

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