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nordicbioscience膠原蛋白形成生物標(biāo)志物

時(shí)間:2020-11-26閱讀:1481
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nordicbioscience膠原蛋白形成生物標(biāo)志物

Extracellular matrix associated biomarkers

Assay name

Assay description

Volume required (uL)

a-SMA

Acetylated N-terminal of alpha-smooth muscle actin

50

BGM

Neo-epitope of MMP-9,12 mediated degradation of biglycan

50

DCN-CS

Cathepsin S mediated decorin degradation

50

HSP47-C

C-terminal of heat shock protein-47

50

LAM

Neo-epitope of MMP-9 mediated degradation of laminin alpha 5 chain

50

LG1M

Neo-epitope of MMP-9 mediated degradation of laminin gamma 1 chain

50

MIM

Neo-epitope of MMP-9,12 mediated degradation of mimecan

50

NIC

Neo-epitope of cathepsin-S mediated degradation of nidogen

50

SPARC-M

Neo-epitope of MMP mediated degracation of SPARC

50

TIM

Neo-epiotpe of MMP-12 mediated degradation of titin (Cardiac isoform)

50

TIM-2

Specific fragment of MMP-12-mediated degradation of titin (Muscle isoform)

50

VCANM

Neo-epitope of MMP-8,12 mediated degradation of versican

50

VICM

Neo- epitope of MMP-2, 8 and trypsin mediated degradation of citrullinated vimentin

50

ARGS

N-terminal epitope of Aggrecanase mediated degradation of aggrecan

50

FBN-C

C-terminal of fibronectin

 

50

CPa9-HNE

Neo-epitope fo human neutrophil elastase (HNE) mediated degradatib if calprotectin

 

50

PROM

Neo-epitope of MMP-1 and -13 mediated degradation of prolargin

50

uPerla

Neo-epiotpe of ADAMTS mediated degradation of perlecan

50

exAGNxI

Neo-epitope of aggrenase mediated aggrecan

50

exFFGV

Neo-epitope of MMP mediated aggrecan

50

BREM

Brevican degraded by MMPs

50

BREV-A

Neo-epitope of ADAMTS-4 mediated degradation of brevican

50

n-BREV

N-terminal of brevican

50

TAU-A

Neo-epitope of ADAM-10 mediated degradation of TAU

50

TAU-C

Neo-epitope of caspase-3 mediated degradation of TAU

50

exMMP3

Activated MMP-3

50

acCAT-K

Activated Cathepsin K

50

acMMP-9

Activated MMP-9

50

acMMP-13

N-terminal of active MMP-13

50

acADAMTS4

N-terminal of active ADAMTS-4

50

acADAMTS5

N-terminal of active ADAMTS-5

50

COMP-N

N-terminal of COMP

50

SPARC-C

C-terminal of SPARC

50

AGR-N

N-terminal of agrin

50

FBN-EDA

Neo-epitope of MMP-8 mediated degradation of cellular fibronectin (EDA domain)

50

FMODM

Fibromodulin degraded by MMP-12

50

Other biomarkers

Assay name

Assay description

Volume required (uL)

GDF-8

Myostatin (growth/differentiation factor 8)

150

IL-6

Interleukin-6

250

FMODM

Fibromodulin degraded by MMP-12

50

Ostase BAP

Bone-specific Alkaline Phosphatase ELISA

100

PIIANP

Type IIA Collagen N-Propeptide (PIIANP) ELISA

10

C-P-Tau (181P)

Phosphorylated Tau (P181)

50

C-β-Amyloid (1-42)

Amyloid Beta 1-42

50

HCG

Chorionic Gonadotropin (pregnancy test)

10

PTH, intact

Parathyroid hormone

50

S-Free T4

thyroxine

15

S-Testosterone

testosterone

20

S-Total T3

Total triiodothyronine

30

S-TSH

thyroid stimulating hormone

50

Total PINP

N-terminal pro-peptide of type I collagen

20

Anti-CCP

Anti-citrullinated protein antibodies

15

Anti-HCV

Antibodies to hepatitis C virus

50

HBsAg II

Hepatitis B surface antigen

50

HIV combi PT

HIV-1 P24 antigen, antibodies against HIV-1 and HIV-2

40

HIV-Ag

HIV-1 P24 antigen group M and O

50

Insulin

Insulin

20

S-Albumin

Albumin

2

S-ALAT

Alanine transaminase

25

S-ASAT

Aspartate transaminase

25

S-Bilirubin

Total billirubin

14.3

S-Calcium

Serum calcium

16

S-Cholesterol

Serum cholesterol

4

S-Creatinine

Serum creatinine

24

S-GGT

Gamma-glutamyltransferase

10

S-Glucose

Glucose

3.4

S-protein

Total serum protein

17.5

S-Urea

Serum urea

7

S-HDL Cholesterol

Serum HDL cholesterol

5

S-LDL Cholesterol

Serum LDL cholesterol

5

Urine Calcium

Urine calcium

16

Urine Creatinine

Urine Creatinine

24

Urine Phosphat

Urine Phosphat

8

S-Phosphat

Serum phosphat

8

S-Magnesium

Serum magnesium

12

S-Lipase

Serum lipase

3

S-Amylase

Serum amylase

16

S-LDH

Serum LDH

14

S-CO2

Serum CO2

6

ELF

 

65

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