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Life Sensors是一家為藥物發(fā)現(xiàn)和研究市場提供方法和建立可行性技術方法的生物技術公司,。該公司為泛素和泛素蛋白酶體通路研究提供創(chuàng)新性的研究工具而占據(jù)世界,。其原核和真核蛋白表達系統(tǒng)SUMOpro 和SUMOstar 已被世界范圍內(nèi)的學術,、政府研究機構(gòu)和制藥,、生物技術公司廣泛應用,。

LifeSensors, Inc., a biotechnology company that discovers and develops enabling technologies for therapeutic, drug discovery and research markets, has established its leadership position by providing innovative research tools for the ubiquitin and ubiquitin-like protein pathways. Its prokaryotic and eukaryotic protein expression platforms SUMOpro and SUMOstar are used worldwide by academic and government institutions, as well as pharmaceutical and biotechnology companies. 
 部分產(chǎn)品信息如下：

PRODUCTS

Expression Systems

Add your protein of interest to the growing bibliography of SUMO-expressed proteins!

Our SUMO-based expression system maximize the yield of soluble, functional proteins in E. coli, yeast, insect and mammalian cells. This system features SUMO functioning as both a chaperonin and as an initiator of protein folding to dramatically improve the solubility and level of expression of your protein of interest. Our desumoylases efficiently and precisely remove SUMO tags, releasing your protein with the desired N-terminal amino acid. Both the SUMO tags and the desumoylases have His6 tags making their subsequent removal fast and easy.

Enhanced Expression and Solubility Using SUMO vs. Other Commonly-used Fusion Tags

Figure legend. GDF8 （myostatin）, a secreted TGFβ family member and difficult-to-express protein, was expressed in E. coli either as a His6, Ub, SUMO, MBP, GST, TRX, or NUS A fusion. Protein fractions were resolved by SDS-PAGE and stained with Coomassie. Arrowheads indicate expected/observed positions of respective protein bands. Of all tags tested, SUMO was the only fusion tag that provided high-level expression of soluble protein.