ODS columns are the most popular columns and used for separations of hydrophobic compounds. The use of ion-pair reagents allows retention and separation of acidic or basic compounds on ODS columns. However, there are several problems associated with ion-pair reagents, for example, the lack of influence of ion-pair reagents on retention, the removal of ion-pair reagents retaind on the column, the use of LC-MS, etc. Hence, TCI developed and commercialised packing materials bearing both ODS ligands capable of firmly retaining hydrophobic compounds and ion-exchange ligands capable of retaining acidic or basic compounds in 1996.
■Target compound is basic → Choose ODS+Cation-Exchange Type
○TCI Dual ODS-CX10 （ODS+Strong Cation Exchange）
○TCI Dual ODS-CX15 （ODS+Medium cation Exchange）
○TCI Dual ODS-CX20 （ODS+Weak Cation Exchange）
Target compound is acidic → Choose ODS+Anion-Exchange Type
○TCI Dual ODS-AX10 （ODS+Strong Anion Exchange）
○TCI Dual ODS-AX20 （ODS+Weak Anion Exchange）
○Kaseisorb LC ODS-SAX （ODS+Strong Anion Exchange）
■Hydrophobic compounds can be retained on mixed-mode columns.
■No ion-pair reagent is required.
■The packing material has both ion-exchange and ODS phases.
（Not a mixture of packing materials of an ion-exchange and ODS）
■High NTP values close to ODS"s.
*** Applications （PDF584KB） *** | Product Name | Analytes, etc. | Specifications | | TCI Dual ODS-CX10 |
Analytes : basic compounds and hydrophobic compounds, catecholamine, melamine, Vitamine B, etc.
| Particle size : 5μm
Pore size : 12nm
pH range : 2.5-7.5
| | TCI Dual ODS-CX20 |
Analytes : basic compounds and hydrohobic compounds, catecholamine, etc.
| Particle size : 5μm
Pore size : 12nm
pH range : 2.5-7.5 （ion exchange range is 4.5-7.5）
| | TCI Dual ODS-AX10 |
Analytes : acidic compounds and hydrohobic compounds, nucleotide, etc.
| Particle size : 5μm
Pore size : 12nm
pH range : 2.5-7.5
| | TCI Dual ODS-AX20 |
Analytes : acidic compounds and hydrohobic compounds, nucleotide, etc.
| Particle size : 5μm
Pore size : 12nm
pH range : 2.5-7.5
| | ODS-CX15 |
Analytes : amino acids, basic compounds and hydrophobic compounds, Serotonin, catecholamine, melamine etc.
| Particle size : 5μm
Pore size : 12nm
pH range : 2.5-7.5
| | Kaseisorb LC ODS-SAX Super |
Analytes : acidic compounds and hydrohobic compounds, aromatic compound, nucleotide, etc.
| Particle size : 5μm
Pore size : 12nm
pH range : 2.5-7.5
| | TCI Dual Guard Column 3mm （Cartridge type） | Special fitting style guard column for protect TCI Dual main column!
For 4.6mmI.D. HPLC column.
Analytes : | Column size : 3mm×15mm
| |
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