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Beclin-1 mouse mAb(5C2)
- 公司名稱 上海貝博生物科技有限公司
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Source
Mouse
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Applications
WB,IHC
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Reactivity
Human,Rat,Mouse
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Dilution
WB 1:1000-2000, IHC 1:100-200
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Storage
-20°C/1 year
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Specificity
Beclin-1 protein detects endogenous levels of BECN1
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Source/Purification
The antibody was affinity-purified from mouse ascites by affinity-chromatography using specific immunogen.
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Immunogen
Synthetic Peptide of Beclin-1 at AA range of 110-190
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Uniprot No
Q14457
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Alternative names
BECN1
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Form
Liquid in PBS containing 50% glycerol, 0.5% BSA and 0.02% sodium azide.
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Clonality
Monoclonal
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Isotype
IgG
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Background
beclin 1(BECN1) Homo sapiens This gene encodes a protein that regulates autophagy, a catabolic process of degradation induced by starvation. The encoded protein is a component of the phosphatidylinositol-3-kinase (PI3K) complex which mediates vesicle-trafficking processes. This protein is thought to play a role in multiple cellular processes, including tumorigenesis, neurodegeneration and apoptosis. Alternative splicing results in multiple transcript variants. [provided by RefSeq, Sep 2015],
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Other
BECN1, BECN1
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Concentration
1 mg/ml
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