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化工儀器網(wǎng)>產(chǎn)品展廳>試劑標(biāo)物>行業(yè)專用試劑>生化與分子生物學(xué)用試劑> MyoD1 Antibody #12344 Cell Signalin...


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進(jìn)口生物試劑,,abcam,cst,,santa

abcam抗體*
abcam抗體* 上??泼羯镤N售MyoD1 Antibody #12344 Cell Signaling,CST原裝品質(zhì),,*,,訂購MyoD1 Antibody #12344 Cell Signaling,詳情請咨詢銷售人員,!
產(chǎn)品詳細(xì)參數(shù)如下>>>>

產(chǎn)品名稱:
貨號:12344
品牌:CST(cell signaling)
抗體來源:Rabbit
克隆類型:Polyclonal
規(guī)格:

No.SizePrice
12344S100 ul (10 western blots)詢價


抗體應(yīng)用:

ApplicationsReactivitySensitivityMW (kDa)Source
W IPH (Mk)Endogenous45Rabbit

Applications Key:  W=Western Blotting  IP=Immunoprecipitation
Reactivity Key:  H=Human  Mk=Monkey
Species cross-reactivity is determined by western blot. Species enclosed in parentheses are predicted to react based on * sequence homology.
特異性/敏感度:MyoD1 Antibody recognizes endogenous levels of total MyoD1 protein. This antibody also detects a 142 kDa protein of unknown origin.
來源及純化方法:Polyclonal antibodies are produced by immunizing animals with a synthetic peptide corresponding to residues surrounding Gly228 of human MyoD1 protein. Antibodies are purified by protein A and peptide affinity chromatography.
抗體背景:

Myoblast determination protein 1 (MyoD1), also called myogenic factor 3 (Myf3), is a member of the MyoD family of muscle­specific bHLH transcription factors (1). This family is responsible for controlling specification of the muscle cell lineage and is expressed only in skeletal muscle and its precursors. MyoD1 is considered a master regulator of skeletal myogenesis as its expression can induce myogenic differentiation in myoblasts, fibroblasts, and a variety of other cell types (2,3). Through ChIP-sequencing experiments, researchers have discovered that MyoD is associated with the promoters of many genes in muscle cells, but it only regulates a subset of those genes. Recent studies point to regulation of MyoD transcriptional activity via epigenetic mechanisms involving SWI/SNF complexes and Polycomb and Trithorax Group proteins (4-6). Additional influences on muscle development include signal transduction through MAPK, PI3K/Akt, myostatin, NF-κB, and mTOR signaling pathways (5-7).

關(guān)鍵詞:CST,,抗體,一抗{byao_back}{byao_back2}

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